Investigator, Howard Hughes Medical Institute
Professor, Biological Chemistry and Physiology
David Geffen School of Medicine
University of California, Los Angeles
Dr. Gonen is an expert in electron crystallography and cryo-EM with more than 20 years experience. He determined the 1.9Å resolution structure of the water channel aquaporin-0 by electron crystallography, the highest resolution for any protein determined by cryo-EM techniques at the time. Dr Gonen established his own laboratory at the University of Washington in 2005 together with the very first cryo-EM laboratory in the Pacific Northwest, a resource that continues to benefit many researchers at the UW School of Medicine and beyond. He has authored many publications from his laboratory concerning membrane protein structure and function. More recently Dr. Gonen was honored with a Career Development award from the American Diabetes Association as well as being chosen one of only 50 Howard Hughes Medical Institute Early Career Scientists around the country. In 2011, Dr. Gonen accepted a position as a Group Leader at the HHMI Janelia Research Campus where he began developing MicroED as a new method for structural biology. With this method, Dr. Gonen has pushed the boundaries of cryo-EM and determined a number of previously unknown structures at resolutions close to 1Å. In 2012, he became a member of the Royal Society of New Zealand.